Fmoc-Lys(Alloc)-OH

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Catalog Number
ACM146982276
Product Name
Fmoc-Lys(Alloc)-OH
Structure
Structure
CAS
146982-27-6
Category
Amino Acids
Description
Orthogonally-protected building block for the synthesis of branched and cyclic peptides and peptides modified at the Lys side chain by Fmoc SPPS. The Alloc group can be selectively removed in the presence of standard Fmoc- and t-butyl-based protecting groups by treatment with Pd(Ph3P)4/CHCl3/AcOH/NMM.
Synonyms
Nα-Fmoc-Nε-Alloc-L-lysine
Molecular Weight
452.5
Molecular Formula
C25H28N2O6
Canonical SMILES
OC(=O)[C@H](CCCCNC(=O)OCC=C)NC(=O)OCC1c2ccccc2-c3ccccc13
InChI
1S/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1
InChI Key
OJBNDXHENJDCBA-QFIPXVFZSA-N
Melting Point
87-91℃
Application
Peptide synthesis.
Assay
≥95.0% (HPLC)
Beilstein
5893081
Color
beige
Form
powder
Functional Group
Fmoc
MDL Number
MFCD00190872
NACRES
NA.26
Optical Activity
[α]20/D -12±1°, c = 1% in DMF
PubChem ID
57651022
Quality Level
100
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-8℃
Technique
NMR: suitable
Type
Unlabeled Standard Amino Acids, Lysine (Lys)
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