Catalog Number
ACM206060540
Product Name
Fmoc-L-(2,6-di-Me)Tyr-OH
Description
Fmoc-2,6-dimethyl-L-tyrosine is a derivative of L-tyrosine, which is one of the 20 naturally occurring amino acids. It is an acronym for 9-Fluorenylmethyloxycarbonyl-2,6-dimethyltyrosine. Fmoc-2,6-dimethyl-L-tyrosine is also referred to as fluorenylmethoxycarbonyl-2,6-dimethyltyrosine or Fmoc-Dmt-OH. Fmoc-Dmt-OH has a molecular weight of 393.45 and a molecular formula of C23H21NO5.
Synonyms
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine, Fmoc-2,6-dimethyl-L-tyrosine, (S)-N-Fmoc-2,6-Dimethyltyrosine
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid
Molecular Formula
C26H25NO5
Canonical SMILES
CC1=CC(=CC(=C1CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C)O
InChI
1S/C26H25NO5/c1-15-11-17(28)12-16(2)22(15)13-24(25(29)30)27-26(31)32-14-23-20-9-5-3-7-18(20)19-8-4-6-10-21(19)23/h3-12,23-24,28H,13-14H2,1-2H3,(H,27,31)(H,29,30)/t24-/m0/s1
InChI Key
RHSSAHKTHNKPGU-DEOSSOPVSA-N
Boiling Point
691.2±55.0 ℃at 760 mmHg
Application
Fmoc-2,6-dimethyl-L-tyrosine has several research applications, including the synthesis of peptides, proteins, and peptidomimetics. It is also used as a building block of combinatorial libraries for the discovery of new drug candidates. Fmoc-2,6-dimethyl-L-tyrosine has been incorporated into various bioactive peptides and proteins to improve their stability, activity, and specificity. It has also been used as a precursor for the synthesis of novel peptidomimetics with potential therapeutic applications.
Type
Unusual Amino Acids, Analogs of Phenylalanine and Tyrosine
Vapor Pressure
0.0±2.3 mmHg at 25℃
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