Fmoc-Hse(Trt)-OH

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Catalog Number
ACM111061553
Product Name
Fmoc-Hse(Trt)-OH
Structure
Structure
CAS
111061-55-3
Category
Amino Acids
Description
Building block which enables side-chain modification of homoserine serines by Fmoc SPPS. The Trt group can be removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This derivative has been employed to prepare oligonucleotide conjugates.
Synonyms
Fmoc-Hse(Trt)-OH, N-α-Fmoc-O-trityl-L-homoserine
Molecular Weight
583.67
InChI
1S/C38H33NO5/c40-36(41)35(39-37(42)43-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34)24-25-44-38(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-23,34-35H,24-26H2,(H,39,42)(H,40,41)/t35-/m0/s1
InChI Key
QUTREFXHXPNEJN-DHUJRADRSA-N
Application
Peptide synthesis.
Assay
≥80.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)
Form
powder
Functional Group
hydroxyl
MDL Number
MFCD00270544
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
15-25℃
Please kindly note that our products are for research use only.

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