Fmoc-Glu-OtBu

• Catalog Number: ACM84793077
• Product Name: Fmoc-Glu-OtBu
• CAS: 84793-07-7
• Category: Amino Acids
• Description: Selectively protected building block for library synthesis or the preparation of γ-glutamyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the γ-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters, amides, lactams and lactones containing the glutamyl unit.
• Synonyms: Fmoc-Glu-OtBu, N-α-Fmoc-L-glutamic acid α-t.-butyl ester
• Molecular Weight: 425.47
• Molecular Formula: C24H27NO6
• InChI: 1S/C24H27NO6/c1-24(2,3)31-22(28)20(12-13-21(26)27)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,27)/t20-/m0/s1
• InChI Key: GOPWHXPXSPIIQZ-FQEVSTJZSA-N
• Melting Point: 105-110℃
• Application: Peptide synthesis.
• Assay: ≥95.0% (acidimetric); ≥98% (TLC); ≥99.0% (HPLC)
• Form: powder
• Functional Group: carboxylic acid
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unlabeled Standard Amino Acids, Glutamic Acid (Glu)