Fmoc-Dab(ivDde)-OH

• Catalog Number: ACM607366212
• Product Name: Fmoc-Dab(ivDde)-OH
• CAS: 607366-21-2
• Category: Amino Acids
• Description: This orthogonally-protected diaminobutyric acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains and from side-chain to γ-amino group.When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group.
• Synonyms: Fmoc-Dab(ivDde)-OH, N-α-Fmoc-N-γ-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-diaminobutanoic acid
• Molecular Weight: 546.65
• InChI: 1S/C32H38N2O6/c1-19(2)15-26(29-27(35)16-32(3,4)17-28(29)36)33-14-13-25(30(37)38)34-31(39)40-18-24-22-11-7-5-9-20(22)21-10-6-8-12-23(21)24/h5-12,19,24-25,35H,13-18H2,1-4H3,(H,34,39)(H,37,38)/t25-/m0/s1
• InChI Key: IMMMALLSYWTSAX-VWLOTQADSA-N
• Application: Peptide synthesis.
• Assay: ≥95.0% (HPLC); ≥98% (TLC)
• Form: powder
• Functional Group: amine
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃