Fmoc-D-Thr[PO(OBzl)-OH]-OH

• Catalog Number: ACM175291562-1
• Product Name: Fmoc-D-Thr[PO(OBzl)-OH]-OH
• CAS: 175291-56-2
• Category: Amino Acids
• Description: Fmoc-O-(benzylphospho)-L-threonine is a phosphopeptide derivative that is used in the synthesis of proteins and peptides. The compound is formed by attaching a benzylphosphonic acid group to the hydroxyl group of the threonine residue. This modification can enhance the stability and specificity of the peptide or protein towards its target. The Fmoc (fluorenylmethoxycarbonyl) group is a common protecting group used in peptide synthesis to prevent unwanted chemical reactions during the coupling of amino acids.
• Synonyms: Fmoc-Thr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-L-phosphothreonine, Fmoc-O-(benzylphospho)-L-threonine
• IUPAC Name: (2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[hydroxy(phenylmethoxy)phosphoryl]oxybutanoic acid
• Molecular Weight: 511.5
• Molecular Formula: C26H26NO8P
• Canonical SMILES: CC(C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OP(=O)(O)OCC4=CC=CC=C4
• InChI: 1S/C26H26NO8P/c1-17(35-36(31,32)34-15-18-9-3-2-4-10-18)24(25(28)29)27-26(30)33-16-23-21-13-7-5-11-19(21)20-12-6-8-14-22(20)23/h2-14,17,23-24H,15-16H2,1H3,(H,27,30)(H,28,29)(H,31,32)/t17-,24+/m0/s1
• InChI Key: HOFDVXHILSPFNS-BXKMTCNYSA-N
• Density: 1.4±0.1 g/cm³
• Application: Fmoc-O-(benzylphospho)-L-threonine has been widely used in scientific experiments to improve the stability and specificity of peptides and proteins towards their targets. The compound has been used in the synthesis of various bioactive peptides, such as antimicrobial peptides, and has shown potential for various biomedical applications.
• Assay: ≥90.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Exact Mass: 511.139618
• Form: powder
• Functional Group: Fmoc
• Impurities: Water (K. F.): ≤ 2.0 %
• LogP: 5.09
• MDL Number: MFCD00797870
• PSA: 141.2
• Quality Level: 200
• Refractive Index: 1.615
• Storage Temperature: 15-25℃
• Type: Unusual Amino Acids, Phosphorylated Amino Acids
• WGK Germany: 3