Fmoc-Cys(Mmt)-OH

• Catalog Number: ACM177582217
• Product Name: Fmoc-Cys(Mmt)-OH
• CAS: 177582-21-7
• Category: Amino Acids
• Description: Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS. Reference 4 describes a novel method for on-resin disulfide bond formation which uses Cys(Mmt) in combination with Cys(tBuS).
• Synonyms: Fmoc-Cys(Mmt)-OH, N-α-Fmoc-S-p-methoxytrityl-L-cysteine
• Molecular Weight: 615.74
• Molecular Formula: C38H33NO5S
• InChI: 1S/C38H33NO5S/c1-43-29-22-20-28(21-23-29)38(26-12-4-2-5-13-26,27-14-6-3-7-15-27)45-25-35(36(40)41)39-37(42)44-24-34-32-18-10-8-16-30(32)31-17-9-11-19-33(31)34/h2-23,34-35H,24-25H2,1H3,(H,39,42)(H,40,41)/t35-/m0/s1
• InChI Key: LOBUWFUSGOYXQX-DHUJRADRSA-N
• Application: Peptide synthesis.
• Assay: ≥85.0% (acidimetric); ≥98.0% (HPLC); ≥99% (TLC)
• Form: powder
• Functional Group: thiol
• MDL Number: MFCD00270541
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃
• Type: Unlabeled Standard Amino Acids, Cysteine (Cys)