Doxorubicin hydrochloride

• Catalog Number: ACM25316409-1
• Product Name: Doxorubicin hydrochloride
• CAS: 25316-40-9
• Category: Inhibitors
• Description: Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
• Molecular Formula: C₂₇H₃₀ClNO₁₁