Dimethyl sulfoxide

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Catalog Number
ACM67685-3
Product Name
Dimethyl sulfoxide
Structure
Structure
CAS
67-68-5
Category
Solvents
Description
Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This Colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high melting point. DMSO has the unusual property that many individuals perceive a garlic-like taste in the mouth after contact with the skin.In terms of chemical structure, the molecule has idealized Cs symmetry. It has a trigonal pyramidal molecular geometry consistent with other three-coordinate S(IV) compounds, with a nonbonded electron pair on the approximately tetrahedral sulfur atom.
Synonyms
DMSO, Methyl sulfoxide, (Methylsulfinyl)methane
IUPAC Name
methanesulfinylmethane
Molecular Weight
78.13
Molecular Formula
C2H6OS
Canonical SMILES
CS(C)=O
InChI
1S/C2H6OS/c1-4(2)3/h1-2H3
InChI Key
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
Boiling Point
189.0±9.0 °C at 760 mmHg
Melting Point
18.4 °C
Flash Point
85.0±0.0 °C
Density
1.1±0.1 g/cm3
Solubility
Miscible in water
Appearance
Colorless liquid
Application
DMSO is used as a solvent for chemical reactions involving salts, especially the Finkelstein reaction and other nucleophilic substitution reactions.
DMSO is used as the mobile phase in high performance liquid chromatography and liquid chromatography coupled to mass spectrometry.
DMSO can be used for spectrophotometric and environmental testing.
DMSO is a polar aprotic solvent used in chemical reactions, polymerase chain reactions, and as a cryoprotectant vitrifying agent to preserve cells, tissues, and organs.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Beilstein
506008
Color
Clear colorless
Complexity
29
Defined Atom Stereocenter Count
0
EC Number
200-664-3
Exact Mass
78.013931
Form
Liquid
Formal Charge
0
Freezing Point
18.4℃
Hazard Codes
Xi:Irritant
Heavy Atom Count
4
HS Code
29309070
Hydrogen Bond Acceptor Count
2
Hydrogen Bond Donor Count
0
In Vitro Studies
DMSO is an organic solvent that is freely miscible with water, lipids and organic agents. These properties allow for exceptional membrane penetration. The mechanism of action of DMSO is thought to be a combination of anti-inflammatory effects, nerve blockade, smooth muscle relaxation, and collagen inhibition.
Isotope Atom Count
0
LogP
-1.35
MDL Number
MFCD00002089
Monoisotopic Mass
78.0139
PSA
36.28
Refractive Index
1.48
Rotatable Bond Count
0
Shipping
Can be shipped at room temperature, where not in use may vary.
Stability
Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials
Storage Conditions
2-8°C
Topological Polar Surface Area
36.3 Ų
Vapor Density
2.7 (vs air)
Vapor Pressure
0.8±0.3 mmHg at 25°C
WGK Germany
1
CATAssayColor ScaleEvapn ResidueMoistureDescriptionTitrable
ACM67685-3A ≤0.1% Bioreagent INQUIRY
ACM67685-3B ≥99.9 % ≤8 ppm (0.0008%) ≤0.10% HPLC grade INQUIRY
ACM67685-3C ≥99.9 % (Corrected for Water) ≤5 ppm ≤0.1 % HPLC grade INQUIRY
ACM67685-3D ≥99.0% (UK sourced material) ≤0.5% INQUIRY
ACM67685-3E ≥99.8% (Corrected for water) ≤5 ppm ≤50 ppm anhydrous INQUIRY
ACM67685-3F ≥99.9% 5ppm, max 0.1%, Max Spectrophotometric Grade INQUIRY
ACM67685-3G ≥99.80 % ≤20 APHA ≤0.001 % ≤0.1 % (Coulometric) for molecular biology, DNAse, RNAse and Protease free INQUIRY
ACM67685-3H ≥99.6 % ≤20 APHA ≤0.2 % Pure INQUIRY
ACM67685-3I ≥99.80 % ≤0.001 % ≤0.005 % (K.F.) for peptide synthesis INQUIRY
ACM67685-3J ≥99.85 % ≤10 APHA ≤0.005 % ≤0.1 % for spectroscopy INQUIRY
ACM67685-3K ≥99.9 % ≤0.01 % ≤0.1 % (Coulometric) ACS reagent ≤0.001 meq/g INQUIRY
ACM67685-3L ≥99.80 % ≤0.001 % ≤0.1 % for HPLC INQUIRY
ACM67685-3M ≥99.70 % ≤0.001 % ≤0.005 % Extra Dry INQUIRY
ACM67685-3N ≥99.50 % ≤10 APHA ≤0.001 % ≤0.1 % for analysis INQUIRY
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