Cycloleucine

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Catalog Number
ACM52528
Product Name
Cycloleucine
Structure
Structure
CAS
52-52-8
Category
Amino Acids
Description
Cycloleucine is a nonmetabolizable amino acid widely used as a building block in peptide synthesis.
Synonyms
1-Aminocyclopentanecarboxylic acid
Molecular Weight
129.16
Molecular Formula
H2NC5H8CO2H
Canonical SMILES
NC1(CCCC1)C(O)=O
InChI
1S/C6H11NO2/c7-6(5(8)9)3-1-2-4-6/h1-4,7H2,(H,8,9)
InChI Key
NILQLFBWTXNUOE-UHFFFAOYSA-N
Melting Point
320 ℃(dec.) (lit.)
Application
Cycloleucine can be used as a building block to synthesize:
Phosphonylmethylaminocyclopentane-1-carboxylic acid by reacting with paraformaldehyde and diethylphosphite via Kabachnik-Field's reaction.
Benzo[b]thiophene-2-carboxylic acid {1-[1-(R)-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethylcarbamoyl]cyclopentyl}-amide, (MEN14268) as potential tachykinin NK2 receptor antagonist.
Assay
0.97
Beilstein
636626
EC Number
200-144-6
Form
crystals
MDL Number
MFCD00001381
NACRES
NA.22
PubChem ID
24890914
Quality Level
100
Reaction Suitability
reaction type: solution phase peptide synthesis
Storage Temperature
2-8℃
Technique
ligand binding assay: suitable
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