Cucurbitacin D

• Catalog Number: ACM3877869
• Product Name: Cucurbitacin D
• CAS: 3877-86-9
• Category: Inhibitors
• Description: Cucurbitacin D is an active component in Trichosanthes kirilowii, disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of the heat shock response. Anti-cancer activity.
• Synonyms: (10α,23E)-2β,16α,20,25-Tetrahydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione
• IUPAC Name: (2S,8S,9R,10R,13R,14S,16R,17R)-17-[(E,2R)-2,6-dihydroxy-6-methyl-3-oxohept-4-en-2-yl]-2,16-dihydroxy-4,4,9,13,14-pentamethyl-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
• Molecular Weight: 516.67
• Molecular Formula: C30H44O7
• Canonical SMILES: C[C@@]12C[C@H]([C@@H]([C@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3C[C@@H](C(=O)C4(C)C)O)C)C)[C@](C)(C(=O)/C=C/C(C)(C)O)O)O
• InChI: InChI=1S/C30H44O7/c1-25(2,36)12-11-21(33)30(8,37)23-19(32)14-27(5)20-10-9-16-17(13-18(31)24(35)26(16,3)4)29(20,7)22(34)15-28(23,27)6/h9,11-12,17-20,23,31-32,36-37H,10,13-15H2,1-8H3/b12-11+/t17-,18+,19-,20+,23+,27+,28-,29+,30+/m1/s1
• InChI Key: SRPHMISUTWFFKJ-QJNWWGCFSA-N
• Boiling Point: 521.47 °C
• Melting Point: 151.5 °C
• Flash Point: 381.4±28.0 °C
• Density: 1.08 g/ml
• Appearance: Powder
• Exact Mass: 516.308716
• Hazard Statements: Xi
• LogP: 1.48
• pKa: 12.66±0.29
• PSA: 132.13000
• Refractive Index: 1.582
• Vapor Pressure: 0.0±4.8 mmHg at 25°C

Custom Q&A

What is the molecular formula of Cucurbitacin D?

The molecular formula of Cucurbitacin D is C30H44O7.

What is the molecular weight of Cucurbitacin D?

The molecular weight of Cucurbitacin D is 516.7 g/mol.

What is the IUPAC name of Cucurbitacin D?

The IUPAC name of Cucurbitacin D is (2S,8S,9R,10R,13R,14S,16R,17R)-17-[(E,2R)-2,6-dihydroxy-6-methyl-3-oxohept-4-en-2-yl]-2,16-dihydroxy-4,4,9,13,14-pentamethyl-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione.

What is the InChI of Cucurbitacin D?

The InChI of Cucurbitacin D is InChI=1S/C30H44O7/c1-25(2,36)12-11-21(33)30(8,37)23-19(32)14-27(5)20-10-9-16-17(13-18(31)24(35)26(16,3)4)29(20,7)22(34)15-28(23,27)6/h9,11-12,17-20,23,31-32,36-37H,10,13-15H2,1-8H3/b12-11+/t17-,18+,19-,20+,23+,27+,28-,29+,30+/m1/s1.

What are the synonyms of Cucurbitacin D?

The synonyms of Cucurbitacin D are Elatericin A, 3877-86-9, Elatericine A, and Cucurbitacine (D).

What is the CAS number of Cucurbitacin D?

The CAS number of Cucurbitacin D is 3877-86-9.

What is the European Community (EC) number of Cucurbitacin D?

The European Community (EC) number of Cucurbitacin D is 686-158-7.

What is the Lipid Maps ID (LM_ID) of Cucurbitacin D?

The Lipid Maps ID (LM_ID) of Cucurbitacin D is LMST01010106.

What is the XLogP3-AA value of Cucurbitacin D?

The XLogP3-AA value of Cucurbitacin D is 2.1.

What is the hydrogen bond donor count of Cucurbitacin D?

The hydrogen bond donor count of Cucurbitacin D is 4.