Catalog Number
ACM2584716-1
Product Name
cis-4-Hydroxy-D-proline
Synonyms
(2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid, D-allo-Hydroxyproline
Canonical SMILES
O[C@H]1CN[C@H](C1)C(O)=O
InChI
1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m1/s1
InChI Key
PMMYEEVYMWASQN-QWWZWVQMSA-N
Melting Point
243 ℃(dec.) (lit.)
Application
Peptide synthesis.
Biochem Physiol Actions
Cis-4-Hydroxy-D-proline may be used as a starting material for the 13-step synthesis of new conformationally restricted PNA adenine monomer and the synthesis of N-Benzyl pyrrolidinyl sordaricin derivatives. Cis-4-Hydroxy-D-proline is a substrate that may be used to study the specificity and kinetics of D-alanine dehydrogenase. Cis-4-Hydroxy-D-proline may be used to analyze the substrate specificity of amino acid transporter PAT1.
Technique
ligand binding assay: suitable