a-3 Hydrochloride

• Catalog Number: ACM78957854
• Product Name: a-3 Hydrochloride
• CAS: 78957-85-4
• Category: Inhibitors
• Description: A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively.
• Synonyms: A3, Hydrochloride, A3 hydrochloride, IN1547, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl, A-3HYDROCHLORIDE, A1980_SIGMA, SCHEMBL3503907, CHEMBL1255867, CTK7E9088, OR0890T, MolPort-001-756-823, CCG-222331, LP01027, NCGC00094317-01, 3B3-053691, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulphonamide hydrochloride, N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, HYDROCHLORIDE, 78957-85-4
• IUPAC Name: N-(2-aminoethyl)-5-chloronaphthalene-1-sulfonamide;hydrochloride
• Molecular Weight: 321.22
• Molecular Formula: C₁₂H₁₄Cl₂N₂O₂S
• InChI Key: VWAGIWCLJAQLAL-UHFFFAOYSA-N
• Melting Point: 173-176ºC
• Exact Mass: 320.01500
• Hazard Statements: Xi: Irritant
• H-Bond Acceptor: 4
• H-Bond Donor: 3
• Safety Description: 26-36