Ni Y1, Wang Y, Kokot S.
Spectrochim Acta A Mol Biomol Spectrosc. 2008 Oct;70(5):1049-59. Epub 2007 Oct 23.A spectrophotometric method for the simultaneous determination of the important pharmaceuticals, pefloxacin and its structurally similar metabolite, norfloxacin, is described for the first time. The analysis is based on the monitoring of a kinetic spectrophotometric reaction of the two analytes with potassium permanganate as the oxidant. The measurement of the reaction process followed the absorbance decrease of potassium permanganate at 526 nm, and the accompanying increase of the product, potassium manganate, at 608 nm. Read More