Rao Y, Su J, Yang C, Yan N, Chen X, Feng X.
Cell Mol Immunol. 2015 May;12(3):342-53. doi: 10.1038/cmi.2014.55. Epub 2014 Jul 21.High-mobility group box (HMGB) proteins, a family of chromatin-associated nuclear proteins, play amazingly multifaceted roles in the immune system of mammals. Thus far, little is known about the nucleocytoplasmic distribution of HMGBs in teleosts. The present study systematically investigated the dynamic localization of all six HMGB proteins in Ctenopharyngodon idella kidney (CIK) cells. Under basal conditions, all HMGBs exclusively localized to the nucleus. Read More