Fani S1, Dehghan F2,3, Karimian H1, Mun Lo K4, Ebrahimi Nigjeh S5, Swee Keong Y5, Soori R2, May Chow K4, Kamalidehghan B6, Mohd Ali H4,7, Mohd Hashim N1,7.
PLoS One. 2016 Aug 16;11(8):e0160836. doi: 10.1371/journal.pone.0160836. eCollection 2016.Monobenzyltin Schiff base complex, [N-(3,5-dichloro-2-oxidobenzylidene)-4-chlorobenzyhydrazidato](o-methylbenzyl)aquatin(IV) chloride, C1, is an organotin non-platinum metal-based agent. The present study was conducted to investigate its effects on MCF-7 cells with respect to the induction of apoptosis and its inhibitory effect against MCF-7 breast cancer stem cells. As determined in a previous study, compound C1 revealed strong antiproliferative activity on MCF-7 cells with an IC50 value of 2. Read More