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Pamam dendrimergeneration-0.5 | CAS Number: 67874-43-5

Catalog Number
ACM67874435
Product Name
Pamam dendrimergeneration-0.5
Structure
CAS Number
67874-43-5
IUPAC Name
tetrasodium 3-[2-[bis(3-oxido-3-oxopropyl)amino]ethyl-(3-oxido-3-oxopropyl)amino]propanoate
Synonyms
n,n’-1,2-ethanediylbis[n-(2-carboxyethyl)-beta-alanintetrasodiumsalt;PAMAM DENDRIMERGENERATION -0.5;tetrasodium N,N-ethylenebis[N-(2-carboxylatoethyl)-beta-alaninate];STARBURST (PAMAM) DENDRIMER, GENERATION;ethylenediaminetetrapropionic acid, tetrasodium
Molecular Weight
436.278
Exact Mass
220.18300
Molecular Formula
C14H20N2O8.4Na
Boiling Point
632.9ºC at 760 mmHg
Melting Point
>350ºC(lit.)
Flash Point
336.5ºC
Purity
96%
InChIKey
CJVPOGPEEJPBFT-UHFFFAOYSA-J
H-Bond Donor
0
H-Bond Acceptor
10
Hazard Statements
Xi
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1Improving the Gene Transfection in Human Embryonic Stem Cells: Balancing with Cytotoxicity and Pluripotent Maintenance.

Luo C1,2, Lü D2, Pan J1, Long M2.

ACS Appl Mater Interfaces. 2016 Apr 6;8(13):8367-75. doi: 10.1021/acsami.6b00353. Epub 2016 Mar 23.

Manipulation of genes in human embryonic stem cells (hESCs) is imperative for their highly potential applications; however, the transduction efficiency remains very low. Although existing evidence revealed the type, size, and zeta potential of vector affect gene transfection efficiency in cells, the systematic study in hESCs is scarce. In this study, using poly(amidoamine) (PAMAM) dendrimers ended with amine, hydroxyl, or carboxyl as model, we tested the influences of size and surface group as well as cytotoxicity and endocytosis on hESC gene transfection. Read More

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Email:
Tel:1-201-478-8534
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Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA