Zeng Y1, Kurokawa Y, Win-Shwe TT, Zeng Q, Hirano S, Zhang Z, Sone H.
J Toxicol Sci. 2016;41(3):351-70. doi: 10.2131/jts.41.351.Polyamidoamine (PAMAM) dendrimers have potential for biological applications as delivery systems for genes, drugs, and imaging agents into the brain, but their developmental neurotoxicity remains unknown. We investigated the effects of PAMAM dendrimers with various surface functional groups and multiple generations on neuronal differentiation using human neural progenitor cells at an equal mass concentration. Read More