Shi XM1,2, Fan GC2, Shen Q1, Zhu JJ2.
ACS Appl Mater Interfaces. 2016 Dec 28;8(51):35091-35098. doi: 10.1021/acsami.6b14466. Epub 2016 Dec 16.Sensitive and accurate analysis of DNA is crucial to better understanding of DNA functions and early diagnosis of fatal disease. Herein, an enhanced photoelectrochemical (PEC) DNA biosensor was proposed based on dual-signal amplification via coupling inorganic-organic nanocomposites sensitization with λ-exonuclease (λ-Exo)-assisted target recycling. The short DNA sequence about chronic myelogenous leukemia (CML, type b3a2) was selected as target DNA (tDNA). Read More