Altenhofen S1, Wiprich MT1, Nery LR1, Leite CE2, Vianna MR3, Bonan CD4.
Aquat Toxicol. 2017 Jan;182:172-183. doi: 10.1016/j.aquatox.2016.11.013. Epub 2016 Nov 17.Manganese (Mn) is an essential metal for organisms, but high levels can cause serious neurological damage. The aim of this study was to evaluate the effects of MnCl2 exposure on cognition and exploratory behavior in adult and larval zebrafish and correlate these findings with brain accumulation of Mn, overall brain tyrosine hydroxylase (TH) levels, dopamine (DA) levels, 3,4-dihydroxyphenylacetic acid (DOPAC) levels and cell death markers in the nervous system. Read More