Losartan

• Catalog Number: ACM114798264
• Product Name: Losartan
• CAS: 114798-26-4
• Category: Heterocyclic Organic Compound
• Synonyms: dup89;LOS;nyl)-4-yl)methyl)-;2-butyl-4-chloro-1-[p-(o-1h-tetrazol-5-ylphenyl)benzyl]imidazole-5- methanol;LOSARTAN;LosartanC22H23C1N60;1h-imidazole-5-methanol, 2-butyl-4-chloro-1-((2-(1h-tetrazol-5-yl)(1,1- biphenyl)-4-yl)methyl)-;(1-((2-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHYL)-2-BUTYL-4-CHLORO-1H-IMIDAZOL-5-YL)METHANOL (LOSARTAN)
• Molecular Weight: 422.91
• Molecular Formula: C₂₂H₂₃ClN₆O
• Melting Point: 183-184 C
• Hazard Statements: Xi
• Safety Description: 26-36

Custom Q&A

What is the molecular formula of Losartan?

The molecular formula of Losartan is C22H23ClN6O.

What is the molecular weight of Losartan?

The molecular weight of Losartan is 422.9 g/mol.

What is the mechanism of action of Losartan?

The mechanism of action of Losartan is as an Angiotensin 2 Receptor Antagonist.

When was Losartan granted FDA approval?

Losartan was granted FDA approval on April 14, 1995.

What is the IUPAC name of Losartan?

The IUPAC name of Losartan is [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol.

What are some synonyms for Losartan?

Some synonyms for Losartan include losartan, DUP 89, allisartan, and Angizaar.

What are the common identifiers for Losartan?

Common identifiers for Losartan include CAS number 114798-26-4, ChEMBL ID CHEMBL191, and KEGG ID D08146.

How is Losartan available for use?

Losartan is available as losartan potassium oral tablets and in combination with hydrochlorothiazide.

How should patients taking Losartan be monitored?

Patients taking Losartan should have their renal function and potassium levels monitored.

What is the chemical safety summary of Losartan?

Losartan is a biphenylyltetrazole and a member of imidazoles with roles as an antihypertensive agent, an angiotensin receptor antagonist, an endothelin receptor antagonist, and an anti-arrhythmia drug.