What is the PubChem CID of Isavuconazole?
The PubChem CID of Isavuconazole is 6918485.
What is the molecular formula of Isavuconazole?
The molecular formula of Isavuconazole is C22H17F2N5OS.
What is the molecular weight of Isavuconazole?
The molecular weight of Isavuconazole is 437.5 g/mol.
What is the structure of Isavuconazole?
The structure of Isavuconazole is a 1,3-thiazole that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,5-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively.
What are the synonyms of Isavuconazole?
The synonyms of Isavuconazole are 241479-67-4, BAL-4815, isavuconazol, and BAL 4815.
What is the ChEBI ID of Isavuconazole?
The ChEBI ID of Isavuconazole is not mentioned in the reference.
What is the approved use of Isavuconazole?
Isavuconazole is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis.
What is the mechanism of action of Isavuconazole?
The mechanism of action of Isavuconazole is as a Cytochrome P450 3A4 Inhibitor, Organic Cation Transporter 2 Inhibitor, and P-Glycoprotein Inhibitor.
What types of fungal infections is Isavuconazole effective against?
Isavuconazole is effective against invasive aspergillosis, mucormycosis, Candida species, Aspergillus species, Mucorales, Cryptococcus spp., Fusarium species, dermatophytes, and dimorphic fungi.
How is Isavuconazole administered?
Isavuconazole can be administered orally or intravenously. The intravenous formulation is cyclodextrin-free and has an advantage over other azole antifungals that require cyclodextrin for drug solubility. The intravenous and oral dosing can be used interchangeably, without the need for a repeat loading dose when transitioning from an IV to an oral formulation.