Catalog Number
ACM158440712
Description
Irofulven is a DNA-damaging and antitumor agent for the treatment of advanced solid tumors, including prostate, ovarian, and pancreatic cancers.
Synonyms
Irofulven; HMAF; MGI 114; NSC-683863; MGI-114; MGI114; NSC 683863; NSC683863
IUPAC Name
(5'R)-5'-Hydroxy-1'-(hydroxymethyl)-2',5',7'-trimethylspiro[cyclopropane-1,6'-indene]-4'-one
Molecular Formula
C15H18O3
Canonical SMILES
O=C([C@@]1(O)C)C2=CC(C)=C(CO)C2=C(C)C31CC3
InChI
InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1
InChI Key
NICJCIQSJJKZAH-AWEZNQCLSA-N
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Storage
Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Drug Formulation
This drug may be formulated in DMSO
Elemental Analysis
C, 73.15; H, 7.37; O, 19.49
HS Tariff Code
2934.99.9001
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage
0-4 °C for short term (days to weeks), or -20 °C for long term (months).