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Ir-140 | CAS Number: 53655-17-7

Catalog Number
ACM53655177
Product Name
Ir-140
Structure
CAS Number
53655-17-7
Synonyms
IR-140;IR 140 (DYE);IR-140 PERCHLORATE;KODAK IR 140;5,5-DICHLORO-3,3-DIETHYL-11-DIPHENYLAMINO-10,12-ETHYLENETHIATRICARBOCYANINE PERCHLORATE;5,5-DICHLORO-11-DIPHENYLAMINO-3,3-DIETHYL-10,12-ETHYLENETHIATRICARBOCYANINE PERCHLORATE;5-CHLORO-2-(2-[3-(2-[5-CHLO
Molecular Weight
779.19
Molecular Formula
C39H34Cl3N3O4S2
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1Phase I pharmacokinetic (PK) & pharmacogenetic study of sequential infusional irinotecan (IR) and fluorouracil (FU).

Grem JL1, Wright M1, Morrison G1, Lin PX1, Leonard G1, Nguyen D1, Guo XD1, Szabo E1; NCI-Navy GI Tumor Clinical Group.

J Clin Oncol. 2004 Jul 15;22(14_suppl):2075.

2075 Background: Preclinical studies show that initial exposure to IR prior to FU is superior to concurrent exposure or the reverse sequence. IR given over 24h may be better tolerated than 0.5-1.5h infusions.METHODS: 32 patient (pts) with GI tract cancers participated. IR was initially given at 4 levels (70-140 mg/m2/24h ) followed by LV 500 mg/m2/0.5h & FU 2000 mg/m2/48h starting d 1 & 15 of a 4-wk cycle. Read More

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Tel:1-201-478-8534
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Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA