Hatada M1, Tsugawa W2, Kamio E1, Loew N3, Klonoff DC4, Sode K5.
Biosens Bioelectron. 2017 Feb 15;88:167-173. doi: 10.1016/j.bios.2016.08.005. Epub 2016 Aug 3.Glycated proteins, such as glycated hemoglobin (HbA1c) or glycated albumin (GA) in the blood, are essential indicators of glycemic control for diabetes mellitus. Since GA, compared to HbA1c, is more sensitive to short term changes in glycemic levels, GA is expected to be used as an alternative or together with HbA1c as a surrogate marker indicator for glycemic control. In this paper we report the development of a sensing system for measuring GA by combining an enzyme analysis method, which is already used in clinical practice, with electrochemical principles. Read More