Herboxidiene

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Catalog Number
ACM142861005
Product Name
Herboxidiene
Structure
Structure
CAS
142861-00-5
Category
Inhibitors
Description
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome.
Synonyms
Herboxidiene
Molecular Weight
438.60
Molecular Formula
C25H42O6
Canonical SMILES
C[C@H]([C@H]([C@H](O)C)OC)[C@@]1([H])O[C@]1(C)C[C@@H](/C=C/C=C(C)/[C@H]2O[C@@H](CC(O)=O)CC[C@@H]2C)C
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
Streptomyces chromofuscus A7847
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