Palanivel A1, Chennaiah A1, Dubbu S1, Mallick A1, Vankar YD2.
Carbohydr Res. 2017 Jan 2;437:43-49. doi: 10.1016/j.carres.2016.11.012. Epub 2016 Nov 23.Activation of sulfoxide as glycosyl donors using AuCl3/AgOTf reagent system has been described. Under optimal reaction conditions, both armed and disarmed glycosyl sulfoxide donors were found to react with a range of primary, secondary, and tertiary alcohol acceptors, and sugar derived glycosyl acceptors to afford the corresponding glycosides in moderate to good yields with predictable selectivity. The reactions are quick (20-60 min), facile at room temperature and the reactions conditions tolerate acid sensitive groups.Copyright © 2016 Elsevier Ltd. All rights reserved.