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Diethyl pyrocarbonate | CAS Number: 1609-47-8

Catalog Number
ACM1609478
Product Name
Diethyl pyrocarbonate
Structure
CAS Number
1609-47-8
Synonyms
DIETHYL PYROCARBONATE;DIETHYL OXYDIFORMATE;DIETHYL DICARBONATE;ETHOXYFORMIC ACID ANHYDRIDE;ETHOXYFORMIC ANHYDRIDE;OXYDIFORMIC ACID DIETHYL ESTER;PYROCARBONIC ACID DIETHYL ESTER;Baycovin
Molecular Weight
162.14
Molecular Formula
C6H10O5
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1Alkyl-substituted phenyl-amino derivatives of 7-nitrobenz-2-oxa-1,3-diazole as uncouplers of oxidative phosphorylation and antibacterial agents: involvement of membrane proteins in the uncoupling action.

Antonenko YN1, Denisov SS2, Khailova LS3, Nazarov PA3, Rokitskaya T3, Tashlitsky VN4, Firsov AM3, Korshunova GA3, Kotova EA5.

Biochim Biophys Acta. 2016 Dec 20. pii: S0005-2736(16)30407-2. doi: 10.1016/j.bbamem.2016.12.014. [Epub ahead of print]

In search for new effective uncouplers of oxidative phosphorylation, we studied 4-aryl amino derivatives of a fluorescent group 7-nitrobenz-2-oxa-1,3-diazol (NBD). In our recent work (Denisov et al., Bioelectrochemistry, 2014), NBD-conjugated alkyl amines (NBD-Cn) were shown to exhibit uncoupling activity. It was concluded that despite a pKa value being about 10, the expected hindering of the uncoupling activity could be overcome by insertion of an alkyl chain. Read More

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Tel:1-201-478-8534
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Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA