Huntosova V1, Stroffekova K, Wagnieres G, Novotova M, Nichtova Z, Miskovsky P.
Metallomics. 2014 Dec;6(12):2279-89. doi: 10.1039/c4mt00190g. Epub 2014 Nov 5.Phototoxicity is a side-effect of in vitro and in vivo oxygen partial pressure (pO2) detection by luminescence lifetime measurement methods. Dichlorotris(1,10-phenanthroline)-ruthenium(ii) hydrate ([Ru(Phen)3]2+) is a water soluble pO2 probe associated with low phototoxicity, which we investigated in vivo in the chick's chorioallantoic membrane (CAM) after intravenous or topical administration and in vitro in normal human coronary artery endothelial cells (HCAEC). Read More