Romanyuk AV1, Zvezdin VN, Samant P, Grenader MI, Zemlyanova M, Prausnitz MR.
Anal Chem. 2014 Nov 4;86(21):10520-3. doi: 10.1021/ac503823p. Epub 2014 Oct 17.Clinical medicine and public health would benefit from simplified acquisition of biological samples from patients that can be easily obtained at point of care, in the field, and by patients themselves. Microneedle patches are designed to serve this need by collecting dermal interstitial fluid containing biomarkers without the dangers, pain, or expertise needed to collect blood. This study presents novel methods to collect biomarker analytes from microneedle patches for analysis by integration into conventional analytical laboratory microtubes and microplates. Read More