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Home > Product > Material & Chemicals > Polymer/Macromolecule > Cyclohexane-1,4-dimethanolmonovinylether

Cyclohexane-1,4-dimethanolmonovinylether | CAS Number: 114651-37-5

Catalog Number
ACM114651375
Product Name
Cyclohexane-1,4-dimethanolmonovinylether
Structure
CAS Number
114651-37-5
EC Number
601-318-8
IUPAC Name
[4-(ethenoxymethyl)cyclohexyl]methanol
Synonyms
1,4-CYCLOHEXANEDIMETHANOL VINYL ETHER;1,4-bis-(hydroxymethyl)-cyclohexane monovinyl ether;4-[(Ethenyloxy)methyl]-cyclohexanemethanol;4-(HYDROXYMETHYL)CYCLOHEXYLMETHYL VINYL ETHER;CYCLOHEXANE-1,4-DIMETHANOLMONOVINYL ETHER;CYCLOHEXANEDIMETHANOL MONOVINYL ET
Molecular Weight
170.25
Exact Mass
170.13100
Molecular Formula
C10H18O2
Boiling Point
262ºC
Melting Point
12ºC
Flash Point
>110ºC
Density
0.986
Purity
96.0
SMILES
C=COCC1CCC(CC1)CO
InChIKey
INRGAWUQFOBNKL-UHFFFAOYSA-N
H-Bond Donor
1
H-Bond Acceptor
2
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1Therapeutic activity of a new antibody-drug immunoconjugate, IMMU-110, in preclinical studies targeted against multiple myeloma.

Stein R1, Griffiths GL1, Cardillo T1, Blumenthal R1, Horak ID1, Goldenberg DM1.

J Clin Oncol. 2004 Jul 15;22(14_suppl):6535.

6535 Background: CD74, a cell-surface-expressed epitope of the HLA class II-associated invariant chain [Ii], is a unique target for antibody-drug immunoconjugate therapy, being a transmembrane chaperone molecule that actively directs transport from the cell surface to an endosomal compartment. IMMU-110 is a drug immunoconjugate comprised of doxorubicin (dox) conjugated to the humanized anti-CD74 monoclonal antibody (MAb), hLL1, at 6-8 drug molecules per IgG molecule. Read More

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