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Home > Product > Material & Chemicals > Polymer/Macromolecule > cis-1,2-Cyclopentanediol

cis-1,2-Cyclopentanediol | CAS Number: 5057-98-7

Catalog Number
ACM5057987
Product Name
cis-1,2-Cyclopentanediol
Structure
CAS Number
5057-98-7
Synonyms
CIS-CYCLOPENTANE-1,2-DIOL;CIS-1,2-CYCLOPENTANEDIOL;CIS-1,2-DIHYDROXYCYCLOPENTANE;TIMTEC-BB SBB008502;1,2-Cyclopentanediol, cis-;(1R,2S)-1,2-Cyclopentanediol;(1S)-Cyclopentane-1α,2α-diol;(1S,2R)-1,2-Cyclopentanediol
Molecular Weight
102.13
Molecular Formula
C5H10O2
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1Isolation, characterization, and nuclease activity of biologically relevant chromium(V) complexes with monosaccharides and model diols. Likely intermediates in chromium-induced cancers.

Bartholomäus R1, Irwin JA, Shi L, Smith SM, Levina A, Lay PA.

Inorg Chem. 2013 Apr 15;52(8):4282-92. doi: 10.1021/ic3022408. Epub 2013 Mar 26.

The stabilization of Cr(V) by biological 1,2-diolato ligands, including carbohydrates, glycoproteins, and sialic acid derivatives, is likely to play a crucial role in the genotoxicity of Cr(VI) and has also been implicated in the antidiabetic effect of Cr(III). Previously, such complexes have been observed by electron paramagnetic resonance (EPR) spectroscopy in living cells or animals, treated with carcinogenic Cr(VI), as well as in numerous model systems, but attempts to isolate them have been elusive. Read More

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