Catalog Number
ACM86361559
Description
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities.
Synonyms
2-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,3-benzenediol;Gnetol
IUPAC Name
2-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol
Molecular Formula
C14H12O4
Canonical SMILES
C1=CC(=C(C(=C1)O)C=CC2=CC(=CC(=C2)O)O)O
InChI
InChI=1S/C14H12O4/c15-10-6-9(7-11(16)8-10)4-5-12-13(17)2-1-3-14(12)18/h1-8,15-18H/b5-4+
InChI Key
DQULNTWGBBNZSC-SNAWJCMRSA-N
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