Cotrimoxazole

CAS
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CAS
8064-90-2
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Purity
100 mg/mL in DMSO
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Catalog Number

ACM8064902

Product Name

Cotrimoxazole

Structure

CAS

8064-90-2

What is the molecular formula of Cotrimoxazole?

The molecular formula of Cotrimoxazole is C24H29N7O6S.

What are the synonyms for Cotrimoxazole?

The synonyms for Cotrimoxazole are sulfamethoxazole & trimethoprim, sulfamethoxazole + trimethoprim, CO-Trimoxazole, and Trimosulfa.

What is the molecular weight of Cotrimoxazole?

The molecular weight of Cotrimoxazole is 543.6 g/mol.

What are the component compounds of Cotrimoxazole?

The component compounds of Cotrimoxazole are trimethoprim (CID 5578) and sulfamethoxazole (CID 5329).

When was Cotrimoxazole created?

Cotrimoxazole was created on March 26, 2005.

What is the approved use of Cotrimoxazole?

Cotrimoxazole is approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain infections, including chronic bronchitis, urinary tract and acute ear infections, enteric infections (such as shigellosis and traveler's diarrhea), and Pneumocystis pneumonia (PCP).

What is the mechanism of action of Cotrimoxazole?

The combination of trimethoprim and sulfamethoxazole in Cotrimoxazole inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim acts as a pyrimidine inhibitor of dihydrofolate reductase, while sulfamethoxazole acts as a sulfamide inhibitor of bacterial dihydrofolate synthase.

What is the broad-spectrum antibacterial activity of Cotrimoxazole?

Cotrimoxazole has broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including Pneumocystis pneumonia in AIDS.