Catalog Number
ACM53230107
Description
Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research.
Synonyms
MEFLOQUINE;MEFLOQUINE INTERMEDIATE;Mefloquin;Metloquine;(11R,2'S)-Mefloquine;(R)-α-[(2S)-2-Piperidyl]-2,8-bis(trifluoromethyl)-4-quinolinemethanol;(11S,2'R)-Mefloquine;(S)-α-[(2R)-2-Piperidyl]-2,8-bis(trifluoromethyl)-4-quinolinemethanol
IUPAC Name
(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol
Molecular Formula
C17H16F6N2O
Canonical SMILES
O[C@H]([C@]1([H])NCCCC1)C2=CC(C(F)(F)F)=NC3=C(C(F)(F)F)C=CC=C32
InChI Key
XEEQGYMUWCZPDN-DOMZBBRYSA-N
Boiling Point
415.7ºC at 760mmHg
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Can be shipped at room temperature, where not in use may vary.
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