DL-Homocysteine

Catalog Number

ACM454295-1

Product Name

DL-Homocysteine

Structure

CAS

454-29-5

Category

Amino Acids

Synonyms

2-Amino-4-mercaptobutyric acid

IUPAC Name

2-Amino-4-sulfanylbutanoic acid

Molecular Weight

135.18

Molecular Formula

HSCH2CH2CH(NH2)COOH

Canonical SMILES

NC(CCS)C(O)=O

InChI

1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)

InChI Key

FFFHZYDWPBMWHY-UHFFFAOYSA-N

Boiling Point

299.7±35.0 °C

Melting Point

232-233 ℃(lit.)

Flash Point

>230 °F

Density

1.149 g/cm³

Solubility

H2O: soluble

Appearance

White to off-white solid

Application

DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague-Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.

Storage

-20 °C

Assay

≥95% (titration)

Beilstein

1721683

Biochem Physiol Actions

Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis.

Complexity

86.1

EC Number

207-222-9

Exact Mass

135.03539970

Form

powder

MDL Number

MFCD00004898

Monoisotopic Mass

135.03539970

NACRES

NA.26

PubChem ID

24895646

Quality Level

200

Refractive Index

1.5480

Storage Temperature

-20℃

Topological Polar Surface Area

64.3 Ų

MSDS

COA

Spec Sheet