187-1, N-WASP INHIBITOR

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Catalog Number
ACM380488277
Product Name
187-1, N-WASP INHIBITOR
Structure
Structure
CAS
380488-27-7
Category
Inhibitors
Description
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein.
Synonyms
CYCLO(LKDFDPDFLFDPLQ)2;187-1, N-WASP INHIBITOR;N-WASP-INHIBITOR, 187-1;M.W. 1784.13 C96H122N18O16
IUPAC Name
187-1, N-WASP inhibitor
Molecular Weight
1784.11
Molecular Formula
C96H122N18O16
Canonical SMILES
C1CC2C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4CCCC4C(=O)NC(C(=O)NC(C(=O)N5CCCC5C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CC6=CC=CC=C6)CCCCN)CCC(=O)N)CC7=CC=CC=C7)CC8=CC=CC=C8)CC9=CC=CC=C9)CCCCN)CCC(=O)N)CC1=CC=CC=C1)CC1=CC=CC=C1
InChI Key
PHTIQAVQWWOKNF-RNEDXEELSA-N
Appearance
Solid
Storage
Sealed storage, away from moisture and light, under nitrogen. Powder-80°C, 2 years; -20°C, 1 year. *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Exact Mass
1782.93000
Shipping
Can be shipped at room temperature, where not in use may vary.
Please kindly note that our products are for research use only.

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