Cytochalasin e

CAS
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CAS
36011-19-5
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Purity
>98%
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Catalog Number

ACM36011195

Product Name

Cytochalasin e

Structure

CAS

36011-19-5

Category

Inhibitors

Description

Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.

Synonyms

(7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl;21,23-dioxa(13)cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,;6,7-epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-[13]cytochalas-13,19-die;CYTOCHALASIN 3;CYTOCHALASIN E;CYTOCHALASIN E, ASPERGI

IUPAC Name

CYTOCHALASIN E

Molecular Weight

495.56

Molecular Formula

C₂₈H₃₃NO₇

Canonical SMILES

CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C

InChI Key

LAJXCUNOQSHRJO-ZYGJITOWSA-N

Boiling Point

705.1ºC at 760 mmHg