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Catalog Number
ACM300817689
Product Name
Bh3i-1
Structure
CAS
300817-68-9
Category
Inhibitors
Description
BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.