Polyglycolide

Catalog Number

ACM26124685-2

Product Name

Polyglycolide

CAS

26124-68-5

Category

Heterocyclic Organic Compound

Description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

Synonyms

PGA, Poly(glycolic acid)

IUPAC Name

2-hydroxyacetic acid

Molecular Weight

76.05g/mol

Molecular Formula

(C2H4O3)n

Canonical SMILES

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI Key

AEMRFAOFKBGASW-UHFFFAOYSA-N

Boiling Point

100 °C

Melting Point

79.5 °C;78-80 °C (alpha-modification); 63 °C (beta-modification, metastable);75-80°C;80 °C

Density

1.53 g/mL at 25 °C (lit.)

Solubility

In water, 1X10+6 mg/L at 25 °C (est);Soluble in ethanol, ethyl ether;Soluble in methanol, acetone, acetic acid;Solubility in water: very good

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.

Color/Form

Colorless, translucent solid;Solid glycolic acid forms colorless, monoclinic, prismatic crystals.;Orthorhombic needles from water; leaves from diethyl ether

Complexity

40.2

Corrosivity

Corrosive

Covalently-Bonded Unit Count

1

Decomposition

Hazardous decomposition products formed under fire conditions. - Carbon oxides;When heated to decomposition it emits acrid smoke and irritating fumes.;100 °C

EC Number

201-180-5;217-693-2;247-326-1

Exact Mass

76.016044g/mol

Features And Benefits

Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

Formal Charge

0

H-Bond Acceptor

3

H-Bond Donor

2

Heavy Atom Count

5

ICSC Number

1537

LogP

-1.11 (LogP);log Kow = -1.11;-1.11;-1.11

MDL Number

MFCD00148011

Monoisotopic Mass

76.016044g/mol

NACRES

NA.23

NSC Number

166

Odor

Odorless

Other Experimental

BP: decomposes;MP: 79.5 °C;Hygroscopic;Heat of combustion: 697.1kJ/mole; heat of solution: -11.5 kJ/mole;Light, straw-colored lliquid, odor like burnt sugar; density: 1.27; mp: 10 °C /Commercial 70% solution/;When heated to decomposition it emits acrid smoke and irritating fumes.;Henry's Law constant = 8.5X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 3.11X10-12 cu cm/molecule-sec at 25 °C (est)

Packaging

1, 5, 10 g in glass bottle

PubChem ID

24869373

Quality Level

100

Rotatable Bond Count

1

RTECS Number

MC5250000

Stability

Stable under recommended storage conditions.

Storage Temperature

2-8°C

UNII

0WT12SX38S

UN Number

3261

Vapor Density

Relative vapor density (air = 1): 2.6

Vapor Pressure

0.02 mmHg;2.0X10-2 mm Hg at 25 °C (extrapolated)

XLogP3

-1.1

MSDS

COA

Spec Sheet