Fmoc-4-amino-(1-carboxymethyl) piperidine

Catalog Number

ACM221352825-1

Product Name

Fmoc-4-amino-(1-carboxymethyl) piperidine

Structure

CAS

221352-82-5

Category

Amino Acids

Description

2-(4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)piperidin-1-yl)acetic acid is a synthetic compound designed as a scaffold for drug discovery. It is commonly referred to as Fmoc-Lys(Dde)-OH in the research community. The compound contains one Lysine (Lys) residue, and the abbreviation Dde stands for the protection group used to prevent the Lysine side chain from reacting during peptide synthesis.

Synonyms

2-(4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)piperidin-1-yl)acetic acid, Fmoc-Lys(Dde)-OH

IUPAC Name

2-[4-(9H-fluoren-9-ylmethoxycarbonylamino)piperidin-1-yl]acetic acid

Molecular Weight

380.4

Molecular Formula

C22H24N2O4

Canonical SMILES

C1CN(CCC1NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

InChI

1S/C22H24N2O4/c25-21(26)13-24-11-9-15(10-12-24)23-22(27)28-14-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,15,20H,9-14H2,(H,23,27)(H,25,26)

InChI Key

VLQJIWJYRZIBMP-UHFFFAOYSA-N

Boiling Point

604.151℃at 760 mmHg

Flash Point

319.179℃

Density

1.323 g/cm³

Application

The versatility of Fmoc-Lys(Dde)-OH has led to its use in various scientific experiments, including peptide synthesis, drug discovery, and chemical biology. Peptides and peptidomimetics containing Fmoc-Lys(Dde)-OH have been used as probes for studying protein-protein interactions, enzyme kinetics, and receptor-ligand binding.

Exact Mass

380.174

Functional Group

Fmoc

LogP

3.4029

MDL Number

MFCD01321021

PSA

78.87

Refractive Index

1.649

Storage Temperature

4 ℃

Type

Unusual Amino Acids, Heterocyclic Amino Acids

MSDS

COA

Spec Sheet