Catalog Number
ACM204715913-1
Product Name
Fmoc-4-(Boc-aminomethyl)-L-phenylalanine
Description
Fmoc-4-(Boc-aminomethyl)-L-phenylalanine is a chemical compound consisting of the amino acid phenylalanine with a tert-butyloxycarbonyl (Boc) protection group on the α-amino group and a 9-fluorenylmethoxycarbonyl (Fmoc) protection group on the side chain carboxyl group. This compound is widely used in peptide synthesis due to its favorable properties, such as ease of synthesis, compatibility with solid-phase peptide synthesis techniques, and low toxicity. Fmoc-4-(Boc-aminomethyl)-L-phenylalanine is also used in a variety of scientific experiments related to peptides, proteins, and drug discovery.
Synonyms
4-(Boc-aminomethyl)-Fmoc-phenylalanine, FMOC-L-4-AMINOMETHYLPHENYLALANINE(BOC), FMOC-S-PHE(4-MENHBOC)-OH, FMOC-PHE(4-CH2NHBOC)-OH, REF DUPL: Fmoc-L-Phe(4-CH2NHBoc)-OH, Fmoc-L-(4-amino(Boc)methyl)Phe-OH, Fmoc-L-Phe(4-CH2NHBoc)-OH
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]propanoic acid
Molecular Formula
C30H32N2O6
Canonical SMILES
CC(C)(C)OC(=O)NCC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
InChI
1S/C30H32N2O6/c1-30(2,3)38-28(35)31-17-20-14-12-19(13-15-20)16-26(27(33)34)32-29(36)37-18-25-23-10-6-4-8-21(23)22-9-5-7-11-24(22)25/h4-15,25-26H,16-18H2,1-3H3,(H,31,35)(H,32,36)(H,33,34)/t26-/m0/s1
InChI Key
QSPDPKLGXGMDAY-SANMLTNESA-N
Boiling Point
734.3±60.0 ℃at 760 mmHg
Application
Fmoc-4-(Boc-aminomethyl)-L-phenylalanine is widely used in peptide synthesis, particularly in the solid-phase peptide synthesis technique. It can also be used in the synthesis of cyclic peptides and peptidomimetics. Additionally, the compound can be used as a building block for the synthesis of other amino acid derivatives and bioactive molecules.
Type
Unusual Amino Acids, Analogs of Phenylalanine and Tyrosine
Vapor Pressure
0.0±2.5 mmHg at 25℃
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