Ilaprazole

Catalog Number

ACM172152362

Product Name

Ilaprazole

Structure

CAS

172152-36-2

Category

Inhibitors

Description

Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor.

Synonyms

Ilaprazole;2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-benzimidazole

Molecular Weight

366.44

Molecular Formula

C₁₉H₁₈N₄O₂S

Canonical SMILES

O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2N1)CC4=NC=CC(OC)=C4C

Appearance

Solid

Storage

Powder-20°C, 3 years; 4°C, 2 years; *The compound is unstable in solutions, freshly prepared is recommended..

Shipping

Can be shipped at room temperature, where not in use may vary.

MSDS

COA

Spec Sheet