(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine

Catalog Number

ACM144119120

Product Name

(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine

Structure

CAS

144119-12-0

Category

Heterocyclic Organic Compound

Synonyms

(R)-DPMPM; [(2R)-1-methylpyrrolidin-2-yl]-diphenyl-methanol; (r)-n-methyl-alpha,alpha-diphenyl-2-pyrrolidinemethanol; AJ-20718; alpha,alpha-Diphenyl-N-methyl-D-prolinol; OR10013; AKOS007930843; (R)-alpha,alpha-Diphenyl-N-methyl-2-pyrrolidinemethanol; ((r)-1-methylpyrrolidin-2-yl)diphenylmethanol; KS-00000IVK;

IUPAC Name

[(2R)-1-methylpyrrolidin-2-yl]-diphenylmethanol;

Molecular Weight

267.372g/mol

Molecular Formula

C18H21NO;

Canonical SMILES

CN1CCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O;

InChI

InChI=1S/C18H21NO/c1-19-14-8-13-17(19)18(20,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17,20H,8,13-14H2,1H3/t17-/m1/s1;

InChI Key

XIJAGFLYYNXCAB-QGZVFWFLSA-N;

Application

Chiral amino alcohol assisted asymmetric, enantioselective, aryl transfer of triphenylboroxin to a set of aryl aldehydes in the presence of chiral amino alcohols derived from (S)-proline.

Pyrrolidinylmethanol compound used for the zinc-catalyzed addition of arylboronic acids to aromatic aldehydes, proceeding in high yields and high enantioselectivities (up to 98% ee).

Storage

0-6°C

Complexity

287

Covalently-Bonded Unit Count

1

Defined Atom Stereocenter Count

1

Exact Mass

267.162g/mol

H-Bond Acceptor

2

H-Bond Donor

1

Heavy Atom Count

20

Monoisotopic Mass

267.162g/mol

Rotatable Bond Count

3

Topological Polar Surface Area

23.5A^2

MSDS

COA

Spec Sheet