Cletoquine oxalate

Catalog Number

ACM14142644

Product Name

Cletoquine oxalate

Structure

CAS

14142-64-4

Category

Inhibitors

Description

Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment.

Synonyms

2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]amino]ethanol Oxalate; (+/-)-Desethylhydroxychloroquine Oxalate;

IUPAC Name

2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol;oxalic acid

Molecular Weight

397.85

Molecular Formula

C₁₈H₂₄ClN₃O₅

Canonical SMILES

CC(CCCNCCO)NC1=C2C=CC(=CC2=NC=C1)Cl.C(=O)(C(=O)O)O

InChI Key

DTVGVTDECKJJJK-UHFFFAOYSA-N

Appearance

Brown Solid

Storage

4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).

Exact Mass

397.14000

H-Bond Acceptor

8

H-Bond Donor

5

Shipping

Can be shipped at room temperature, where not in use may vary.

MSDS

COA

Spec Sheet