N-Ethylmaleimide

Catalog Number

ACM-MO-128530

Product Name

N-Ethylmaleimide

Structure

CAS

128-53-0

Category

Inhibitors

Description

N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides.

Synonyms

NEM

IUPAC Name

1-ethylpyrrole-2,5-dione

Molecular Weight

125.13 g/mol

Molecular Formula

C6H7NO2

Canonical SMILES

CCN1C(=O)C=CC1=O

InChI Key

HDFGOPSGAURCEO-UHFFFAOYSA-N

Boiling Point

210 °C

Melting Point

46 °C

Flash Point

73ºC

Density

1.207 g/cm³

Solubility

Soluble in water.

Appearance

White Powder to Crystal

Storage

0-10 °C

Condition To Avoid

Light Sensitive,Air Sensitive,Heat Sensitive

EC Number

204-892-4

Exact Mass

125.04800

Hazard Statements

T+:Verytoxic;

Packing Group

II

Physical State

Solid

Safety Description

S26-S28-S36/37/39-S45

Shipping

Can be shipped at room temperature, where not in use may vary.

Stability

Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate.

WGK Germany

3

MSDS

COA

Spec Sheet