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Catalog Number
ACM125974723
Product Name
Intoplicine
Structure
CAS
125974-72-3
Category
Inhibitors
Description
Intoplicine (RP 60475), an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor. Intoplicine strongly binds DNA (KA = 2 x 105 /M) and thereby increases the length of linear DNA.
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