Mahoney CM1, Fahey AJ, Belu AM.
Anal Chem. 2008 Feb 1;80(3):624-32. doi: 10.1021/ac701644j. Epub 2008 Jan 8.Cluster secondary ion mass spectrometry (cluster SIMS) employing an SF5+ polyatomic primary ion sputter source in conjunction with a Bi3+ analysis source was used to obtain three-dimensional molecular information in polymeric-based drug-eluting stent coatings. The formulations of the coatings varied from 0% to 50% (w/w) sirolimus drug in poly(lactic-co-glycolic acid) and were prepared on both MP35N metal alloy coupons and bare metal stents. Read More