Pantan R1, Onsa-Ard A2, Tocharus J3, Wonganan O4, Suksamrarn A4, Tocharus C5.
Life Sci. 2014 Oct 22;116(1):31-6. doi: 10.1016/j.lfs.2014.08.010. Epub 2014 Aug 21.AIMS: The aim of this study is to investigate the vasorelaxant effect of 16-O-acetyldihydroisosteviol (ADIS) and its underlying mechanisms in isolated rat aorta.MAIN METHODS: Rat aortic rings were isolated, suspended in organ baths containing Kreb's solution, maintained at 37°C, and mounted on tungsten wire and continuously bubbled with a mixture of 95% O2 and 5% CO2 under a resting tension of 1g. The vasorelaxant effects of ADIS were investigated by means of isometric tension recording experiment. Read More