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Home > Product > Material & Chemicals > Metal & Ceramic Materials > Ammonium tetrathiotungstate

Ammonium tetrathiotungstate | CAS Number: 13862-78-7

Catalog Number
ACM13862787
Product Name
Ammonium tetrathiotungstate
Structure
CAS Number
13862-78-7
Synonyms
AMMONIUM THIOTUNGSTATE;AMMONIUM TETRATHIOTUNGSTATE;AMMONIUM TETRATHIOTUNGSTATE (VI);AMMONIUM TETRATHIOTUNGSTATE, 99.9+%;Ammoniumtetrathiotungstate(VI),99%(99.9+%-W);AMMONIUM TETRATHIOTUNGSTATE(VI)*** S. AMMONIUM SECTION;AMMoniuM tetrathiotungstate(VI) (99
Molecular Weight
348.18
Molecular Formula
H8N2S4W
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1Inhibitory effect of ammonium tetrathiotungstate on tyrosinase and its kinetic mechanism.

Park KH1, Lee JR, Hahn HS, Kim YH, Bae CD, Yang JM, Oh S, Bae YJ, Kim DE, Hahn MJ.

Chem Pharm Bull (Tokyo). 2006 Sep;54(9):1266-70.

Tyrosinase requires two copper ions at the active site, in order to oxidize phenols to catechols. In this study, the inhibitory effect of the copper-chelating compound, ammonium tetrathiotungstate (ATTT), on the tyrosinase activity was investigated. ATTT was determined to inactivate the activity of mushroom tyrosinase, in a dose-dependent manner. The kinetic substrate reaction revealed that ATTT functions as a kinetically competitive inhibitor in vitro, and that the enzyme-ATTT complex subsequently undergoes a reversible conformational change, resulting in the inactivation of tyrosinase. Read More

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Tel:1-201-478-8534
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Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA